Multi-dose vial: difference between revisions
Diff·revision 23 → 24·08:24, 29 Jan 2026
Difference between revision 23 and revision 24 of Multi-dose vial. 2 lines changed; the page grew by 464 bytes.
| Revision 23 — 15:08, 8 Jan 2026 BUD_Bertram (talk) close an unbalanced quotation mark 23,705 bytes ±0 | Revision 24 — 08:24, 29 Jan 2026 GramsNotUnitsGil (talk) expand §Antimicrobial preservatives 24,169 bytes +464 | ||
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| 132 | The date of first puncture is a record created by the user rather than by the manufacturer, and the entire dating framework depends on it. Guidance therefore treats annotation of the container at first entry as the mechanism by which the rule is enforceable, since a vial with no such annotation cannot be shown to be within its period and is to be discarded on that ground alone.{{r|usp797,cdc_injection}} | 132 | The date of first puncture is a record created by the user rather than by the manufacturer, and the entire dating framework depends on it. Guidance therefore treats annotation of the container at first entry as the mechanism by which the rule is enforceable, since a vial with no such annotation cannot be shown to be within its period and is to be discarded on that ground alone.{{r|usp797,cdc_injection}} |
| 133 | 133 | ||
| + | 134 | For reconstituted preparations the equivalent record is the reconstitution date, the diluent used and the concentration achieved. None of these is derivable later from the vial: a reconstituted solution offers no visual evidence of its concentration, its diluent or its age. This is the practical reason that the absence of such a record is treated in compounding practice as equivalent to an expired preparation rather than as a documentation lapse.{{r|usp797}} | |
| + | 135 | ||
| 134 | == References == | 136 | == References == |
| 135 | {{reflist}} | 137 | {{reflist}} |