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Peptide stability table: difference between revisions

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Revision 16 — 22:05, 16 Jun 2025
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38'''The assay differs.''' A stability-indicating [[High-performance liquid chromatography|HPLC]] method that resolves the principal degradant reports loss that a method which co-elutes it does not. [[Analytical method validation|Method validation]] is what establishes that a method is stability-indicating, and research-compound figures rarely state whether it was.{{r|ich}}38'''The assay differs.''' A stability-indicating [[High-performance liquid chromatography|HPLC]] method that resolves the principal degradant reports loss that a method which co-elutes it does not. [[Analytical method validation|Method validation]] is what establishes that a method is stability-indicating, and research-compound figures rarely state whether it was.{{r|ich}}
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+40'''The container differs.''' Adsorption to glass, extractables from a stopper, and headspace oxygen all affect degradation rate. A figure obtained in a Type I glass vial with a coated stopper does not transfer to an uncoated one.
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40== References ==42== References ==
41{{reflist}}43{{reflist}}