Syringe dead space: difference between revisions
Diff·revision 17 → 18·06:49, 28 Jan 2026
Difference between revision 17 and revision 18 of Syringe dead space. 7 lines changed; the page grew by 852 bytes.
| Revision 17 — 21:58, 17 Jan 2026 ColdChainCleo (talk) add the sharps-disposal cross-link 18,162 bytes +1,613 | Revision 18 — 06:49, 28 Jan 2026 SigFigSindri (talk) add the note about drawing air before withdrawal 19,014 bytes +852 | ||
|---|---|---|---|
| 126 | * '''Extended plunger tip.''' The plunger tip carries a projection that enters the hub. Values are intermediate and depend on the fit achieved. | 126 | * '''Extended plunger tip.''' The plunger tip carries a projection that enters the hub. Values are intermediate and depend on the fit achieved. |
| 127 | 127 | ||
| + | 128 | Trade-offs are documented. Permanently attached needles cannot be exchanged between withdrawal and injection, which is inconvenient when a wide-bore needle is wanted for withdrawal from a stoppered vial and a fine one for injection. Fine permanently attached needles are also slower to draw viscous liquids and are more easily bent or blunted by passage through an elastomeric closure, a route by which [[Multi-dose vial|stopper coring]] becomes more likely.{{r|who2015}} | |
| + | 129 | ||
| 128 | == Measurement and standards == | 130 | == Measurement and standards == |
| 129 | Dead space is not itself a specified parameter in the principal device standards. ISO 7886-1 specifies the graduated capacity, the tolerance on delivered volume, dimensional requirements, freedom from leakage and the force required to operate the plunger; ISO 8537 does the equivalent for insulin syringes; ISO 7864 covers needles and ISO 9626 the stainless-steel tubing from which they are made. None sets a maximum retained volume, and none requires it to be declared.{{r|iso7886,iso8537,iso7864,iso9626}} | 131 | Dead space is not itself a specified parameter in the principal device standards. ISO 7886-1 specifies the graduated capacity, the tolerance on delivered volume, dimensional requirements, freedom from leakage and the force required to operate the plunger; ISO 8537 does the equivalent for insulin syringes; ISO 7864 covers needles and ISO 9626 the stainless-steel tubing from which they are made. None sets a maximum retained volume, and none requires it to be declared.{{r|iso7886,iso8537,iso7864,iso9626}} |
| ⋮ | ⋮ | ||
| 146 | <ref name="ppdeadspace">PeptidePedia community device-measurement tally, 2026 (self-reported, uncalibrated balances, protocol not controlled; weak evidence — see [[Project:Sourcing_guidelines]]).</ref> | 148 | <ref name="ppdeadspace">PeptidePedia community device-measurement tally, 2026 (self-reported, uncalibrated balances, protocol not controlled; weak evidence — see [[Project:Sourcing_guidelines]]).</ref> |
| 147 | 149 | ||
| + | 150 | == Further reading == | |
| + | 151 | * World Health Organization and UNAIDS. ''Technical Brief: Low Dead Space Syringes'' — the public-health framing of the parameter. | |
| + | 152 | * Frid AH, Kreugel G, Grassi G, et al. "New insulin delivery recommendations." ''Mayo Clinic Proceedings'' 91(9):1231–1255 (2016) — needle length and technique, with dead space treated in passing. | |
| + | 153 | ||
| 148 | == See also == | 154 | == See also == |
| 149 | * [[Insulin syringe]] | 155 | * [[Insulin syringe]] |
| ⋮ | ⋮ | ||
| 153 | * [[Reconstitution calculator]] | 159 | * [[Reconstitution calculator]] |
| 154 | * [[Multi-dose vial]] | 160 | * [[Multi-dose vial]] |
| + | 161 | * [[Sharps disposal]] | |
| 155 | 162 | ||
| 156 | {{DEFAULTSORT:Syringe dead space}} | 163 | {{DEFAULTSORT:Syringe dead space}} |