Syringe dead space: difference between revisions
Diff·revision 19 → 20·04:38, 19 Feb 2026
Difference between revision 19 and revision 20 of Syringe dead space. 10 lines changed; the page grew by 904 bytes.
| Revision 19 — 00:30, 9 Feb 2026 ThymosinTamsin (talk) split overlong sentence 19,381 bytes +367 | Revision 20 — 04:38, 19 Feb 2026 CostPerMgCory (talk) copyedit 20,285 bytes +904 | ||
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| 137 | Community-collated measurements of devices commonly used with reconstituted research peptides exist but are self-reported, use domestic balances of unstated calibration status, and do not control for the protocol variables above. They are consistent with the published device classes in magnitude and are not adequate to support finer distinctions.{{r|ppdeadspace}} | 137 | Community-collated measurements of devices commonly used with reconstituted research peptides exist but are self-reported, use domestic balances of unstated calibration status, and do not control for the protocol variables above. They are consistent with the published device classes in magnitude and are not adequate to support finer distinctions.{{r|ppdeadspace}} |
| 138 | 138 | ||
| + | 139 | == Terminology and reporting problems == | |
| + | 140 | Three recurring problems make the topic harder to read about than its physics warrants. | |
| + | 141 | ||
| + | 142 | The first is the conflation described above: a dead-space volume is quoted as though it were automatically a dose error. It is only a dose error under a specific condition — gas occupying the dead space when the dose is measured — and the condition is often left implicit. | |
| + | 143 | ||
| + | 144 | The second is the use of dead space as a device-quality claim. A device may be marketed on a low retained volume without stating how the figure was obtained, and because no standard requires the declaration, no comparability can be assumed. Marketing figures and gravimetrically measured figures for the same product have differed.{{r|zule2013}} | |
| + | 145 | ||
| 139 | == References == | 146 | == References == |
| 140 | {{reflist}} | 147 | {{reflist}} |
| ⋮ | ⋮ | ||
| 153 | * World Health Organization and UNAIDS. ''Technical Brief: Low Dead Space Syringes'' — the public-health framing of the parameter. | 160 | * World Health Organization and UNAIDS. ''Technical Brief: Low Dead Space Syringes'' — the public-health framing of the parameter. |
| 154 | * Frid AH, Kreugel G, Grassi G, et al. "New insulin delivery recommendations." ''Mayo Clinic Proceedings'' 91(9):1231–1255 (2016) — needle length and technique, with dead space treated in passing. | 161 | * Frid AH, Kreugel G, Grassi G, et al. "New insulin delivery recommendations." ''Mayo Clinic Proceedings'' 91(9):1231–1255 (2016) — needle length and technique, with dead space treated in passing. |
| + | 162 | ||
| + | 163 | == External links == | |
| + | 164 | * [https://www.iso.org/ ISO 7886 series (catalogue entry)] — Device standards for single-use hypodermic syringes. Paywalled. | |
| 155 | 165 | ||
| 156 | == See also == | 166 | == See also == |